CRESTOR (rosuvastatin calcium) is a medication prescribed to treat low cholesterol in patients with one or all of the following conditions:
- Atherosclerosis, to slow the progression
- History of heart attack, stroke, or arterial revascularization in patients with congenital heart disease (CHD)
- Primary hyperlipidemia and mixed dyslipidemia
- Homozygous familial hypercholesterolemia
CRESTOR works by inhibiting HMG-CoA reductase, which is an enzyme that helps to produce mevalonate, a precursor of cholesterol. CRESTOR also works by reducing the number of LDL (low-density lipoprotein) and VLVL (very low-density lipoprotein).
Reducing cholesterol has been shown to lower the chance of cardiovascular events like heart attack and stroke.
For adults, the normal dose range of CRESTOR is 5 mg to 40 mg by mouth once daily. CRESTOR can be taken with or without food and can be taken at any time of day.
In pediatric patients between the ages of 10 to 17, the normal dose range is 5 mg to 20 mg by mouth once daily with or without food. Doses above 20 mg have not been studied in pediatric patients.
The active ingredient in Crestor is rosuvastatin calcium, which is also the name for CRESTOR generic.
CRESTOR and other statin medications can cause a serious side effect called rhabdomyolysis, which is the abnormal breakdown of muscle tissue. Tell your doctor or pharmacist if you experience muscle aches and weakness while taking CRESTOR. Other symptoms may include muscle pain, tenderness, and dark urine.
Your doctor should monitor your liver enzymes while you are taking CRESTOR because it can cause transient increases in liver enzymes.
Some of the most common adverse effects may include:
- Abdominal pain